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Dr
Like other calcium channel blockers, verapamil acts by blocking the influx of calcium ions into vascular smooth muscle and cardiac muscle cells during membrane safety of long-term combination therapy of verapamil and enalapril and its effects on both left ventricular function and myocardial perfusion compared with enalapril alone in 18 patients with DCM (15 men, 3 women; mean age, 50 ± 9 years) without overt heart failure (NYHA class I-II)
14 Nasal civamide, 50 mcg, may be modestly effective as prophylaxis for episodic cluster headache, but it is not A 16-year-old boy who took long-term verapamil after a Mustard operation for transposition of the great arteries developed severe congestive heart failure, which did not respond to diuretics
low blood pressure
The Food and Drug Administration (FDA) approved indications for verapamil include angina (chronic stable, vasospastic or Prinzmetal variant), unstable angina (crescendo, preinfarction), hypertension as add-on therapy, paroxysmal supraventricular tachycardia (PSVT) prophylaxis, and supraventricular tachycardia (SVT)
Co-medication with prednisolone, which is also transported by P-gp, may therefore induce a drug–drug interaction with verapamil
2012 AHS/AAN Guidelines for Migraine Prevention in Adults
The calcium channel blocking agent verapamil (Calan SR, Verelan) is often the first choice for preventing cluster headache
They stop calcium from entering the cells of the heart and arteries
In a 4-month randomized, double-blind, placebo-controlled trial, the frequency of paroxysmal supraventricular tachycardia fell from 0
Verapamil is a non-dihydropyridine calcium channel blocker